Molecular and Cellular Bioengineering Research Experiences for Undergraduates (REU) Program
BlOOD COAGULATION-INDUCING NANOSTRUCTURED Polymer HYDROGEL
We are aiming to develop purely synthetic polymer hydrogels, which are able to actively induce the body’s natural haemostatic coagulation process resulting in the generation of a fibrin- based haemostatic plug in an acellular environment. There is currently no synthetic, polymer-based haemostatic agent with the capability of inducing the formation of a natural haemostatic matrix in the absence of platelets or blood cells, typically vital to the body’s natural haemostatic process. The polymer hydrogels are able to induce the formation of a natural haemostatic plug in the absence of platelets or cells, and have enormous potential as a general haemostatic, especially with patients will platelet disorders. This synthetic haemostatic system is able to achieve the same end result as biological based haemostatics, yet without the innate risk of disease transmission or immunological response, and at a fraction of the price.
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