Control of micro-scale systems, fluid dynamics, biochemicals.
Ph.D., California Institute of Technology, 1999
Dr. Benjamin Shapiro received his bachelors degree from the Aerospace Engineering department at the Georgia Institute of Technology, and his Ph.D. in Control and Dynamical Systems from Caltech. He has been at the University of Maryland since 2000, and joined the Fischell Department of Bioengineering in 2010. His research is focused on modeling, design, and control of micro-scale systems for chemical, biological, and clinical applications. He holds a joint appointment with the Institute for Systems Research and the Maryland NanoCenter, and is affiliated with the Applied Math and Scientific Computation program.
Dr. Shapiro is the recipient of a 2003 NSF CAREER award, and a Fulbright Scholarship. He has filed16 patents based on his research, two of which were awarded 1st and 3rd places in the university's annual Office of Technology Commercialization's Invention of the Year competition. He was born in Jerusalem, Israel in 1973.
Honors and Awards
- 2009 Fulbright Scholar (to Germany) for precision control of magnetic drug delivery to focus chemotherapy to deep tissue tumors. Host: Andreas Lubbe, Director Cecilienklinik (a 750 bed hospital), Bad Lippspringe, Germany.
- 2007-2008 Outstanding Professor AIAA award. Each year students in the Aerospace department vote for the “… professor deemed to be the best teacher in courses over the past academic year”.
- 2007, nominated by Maryland Science Academy for Outstanding Young Engineer award.
- 2006, selected for membership in Council of Outstanding Young Engineering Alumni, Georgia Institute of Technology. Membership is reserved for alumni of the engineering college under forty years of age who have distinguished themselves through professional practice and or service to GT, the profession, or society-at-large.
- 2005-2006 Outstanding Professor AIAA award.
* For a complete list of honors and awards, please visit Professor Shapiro's web site
- Applied Math and Scientific Computation Program
Books and Chapters
Chapters in books
F.Yesilkoy, C.Ropp, Z.Cummins, R.Probst, E.Waks, B.Shapiro, M.Peckerar*, “New Applications and Emerging Technologies”, editor M.Feldman, chapter in “Nanolithograpy: The Art of Fabricating Nanoelectronic, Nanophotonic, and Nanobiologic Devices and Systems”, Woodhead Publishing LTD, Cambridge, 2012.
M.Armani*, Z.Cummins*, J.Gong, P.Mathai*, R.Probst*, C.Ropp, E.Waks, S.Walker*, B.Shapiro, “Feedback Control of Micro-Flows”, chapter for “Control of MEMS to Atoms”, editors J.Gorman and B.Shapiro, Springer Verlag, 2012.
A.Komaee*, R.Lee, A.Nacev*, R.Probst*, A.Sarwar*, I.Rutel, D.Depireux, K.Dormer, B.Shapiro, “Putting Therapeutic Nanoparticles Where They Need To Go By Magnet Systems Design and Control”, editor TK Thanh, chapter in “Magnetic Nanoparticles: From Fabrication to Biomedical and Clinical Applications”, CRC Press/Taylor & Francis, Jan, 2012.
M.Armani*, R.Probst*, B.Shapiro, “Fabricating Micro-Fluidic Channels Using a Vinyl Sign Plotter", chapter for “Lab on a Chip Technology: Fabrication and Microfluidics”, editors K.E.Herold, A.Rasooly, Caister Academic Press, Aug 2009.
B.Shapiro, “Control of Microfluidics” chapter entry for “Encyclopedia of Microfluidics and Nanofluidics”, editor D. Li. Springer Verlag, Sep 2008.
For a complete list of publications, please visit Professor Shapiro's web site.
C.Ropp, Z.Cummins, S.Nah, J.T.Fourkas, B.Shapiro, E.Waks, "Nanoscale Imaging and Spontaneous Emission Control with a Single Nano-Positioned Quantum Dot", Nature Communications, vol 4, article number 1447, doi: 10.1038/ncomms2477, 5 Feb 2013
P.Mathai, P.T.Carmichael, B.Shapiro, J.A.Liddle, "Simultaneous Positioning and Orientation of Single Nano-Objects Using Flow Control", RSC Advances, 2013, vol 3, no 8, pg 2677 - 2682, Jan 2013.
Z.Shen, A.Nacev, A.Sarwar, R.Lee, D.Depireux, B.Shapiro, "Automated Fluorescence and Reflectance Co-Registered 3-D Tissue Imaging System", IEEE Transactions on Magnetics, vol 49, no 1, pg 279-284, Jan 2013.
A.Sarwar, R.Lee, D.Depireux, B.Shapiro, "Magnetic Injection of Nanoparticles into Rat Inner Ears at a Human Head Working Distance", IEEE Transactions on Magnetics, vol 49, no 1, pg 440-452, Jan 2013.
J.B.Freund, B.Shapiro, "Transport of Particles by Magnetic Forces and Cellular Blood Flow in a Model Microvessel", Physics of Fluids, vol 24, pg 051904-1 - 12, published online 29 May 2012.
A.Nacev, R.Probst, S.Kim, A.Komaee, A.Sarwar, R.Lee, D.Depireux, M.Emmert-Buck, B. Shapiro*, "Towards Control of Magnetic Fluids in Patients: Directing Therapeutic Nanoparticles to Disease Locations", IEEE Control System Magazine (CSM), vol 32, no 3, pg 32-74, June 2012. [Invited tutorial paper. With authorship and North/South labels corrected in Fig 6a]. Movies.
R.Probst, Z.Cummins, C.Ropp, E.Waks, B.Shapiro*, "Flow Control of Small Objects On-Chip: Manipulating Live Cells, Quantum Dots, and Nano-Wires", IEEE Control System Magazine (CSM), vol 32, no 2, pg 26-53, April 2012. [Invited tutorial paper.] Movies.
A.Komaee, B.Shapiro*, "Steering a Ferromagnetic Particle by Optimal Magnetic Feedback Control", IEEE Transactions on Control Systems Technology, vol 20, issue 4, pg 1011-1024, July 2012.
A.Sarwar*, A.Nemirovski, B.Shapiro, “Optimal Halbach Permanent Magnet Designs for Maximally Pulling and Pushing Nanoparticles”, Journal of Magnetism and Magnetic Materials (JMMM), vol 324, issue 5, pg 742-754, March 2012.
A.Nacev*, S.H.Kim*, J.Rodriguez-Canales, M.Tangrea, B.Shapiro, M.R. Emmert-Buck “A Dynamic Magnetic Shift Method to Increase Nanoparticle Concentration in Cancer Metastases: A Feasibility Study using Simulations on Autopsy Specimens”, International Journal of Nanmedicine (IJN), vol 2011:6, pg 2907-2923, Nov 2011.
M.Armani*, M.Tangrea, B.Shapiro, M.Emmert-Buck, E. Smela, “Quantifying mRNA Levels Across Tissue Sections with 2D-RT-qPCR”, Analytical and Bioanalytical Chemistry, vol 400, pg 3383-93, July 2011.
R.Probst*, J.Lin*, A.Komaee*, A.Nacev*, Z.Cummins*, B.Shapiro, “Planar Steering of a Single Ferrofluid Drop by Optimal Minimum Power Dynamic Feedback Control of Four Electromagnets at a Distance”, Journal of Magnetism and Magnetic Materials (JMMM), vol 323, pp 885-896, April 2011.
A.Nacev*, C.Beni, O.Bruno, B.Shapiro, “The Behaviors of Ferro-Magnetic Nano-Particles In and Around Blood Vessels under Applied Magnetic Fields”, Journal of Magnetism and Magnetic Materials (JMMM), vol 323, issue 6, pg 651-668, March 2011.
R.Probst*, B.Shapiro, “Three-Dimensional Electrokinetic Tweezing: Device Design, Modeling, and Control Algorithms”, Journal of Micromechanics and Microengineering, vol 21, no 2 article-number 027004, Jan 2011
P.Mathai*, A.Berglund, A.Liddle, B.Shapiro, “Simultaneous Positioning and Orientation of a Single Nano-Object by Flow Control”, New Journal of Physics, vol 13, pg 013027, Jan 2011.
A.Nacev*, C.Beni, O.Bruno, B.Shapiro, “Magnetic Nanoparticle Transport within Flowing Blood and into Surrounding Tissue”, Nanomedicine, vol 5, no 9, pg 1459-1466, Nov 2010.
C.Ropp, Z.Cummins*, R.Probst*, S.Qin, J.Fourkas, B.Shapiro, E.Waks, “Positioning and Immobilization of Individual Quantum Dots with Nanoscale Precision”, NanoLetters, 10(11), pg 4673-4679, Oct 2010.
C.Ropp, R.Probst*, Z.Cummins*, R.Kumar, A.Berglund, S.Srinivasan, E.Waks, B.Shapiro, “Manipulating Quantum Dots to Nanometer Precision by Control of Flow”. NanoLetters, 10 (7), pp 2525–2530, May 2010.