Associate Professor Bruce Yu
Joint appointment with the School of Pharmacy, University of Maryland Baltimore
Ph.D., Johns Hopkins University, 1996.
E-mail: byu@rx.umaryland.edu
Fischell Department of Bioengineering (College Park) contact information:
Room 1130 Jeong H. Kim Engineering Building
Phone: (301) 405-2829
School of Pharmacy (Baltimore) contact information:
Room 635 Health Sciences Facility II
Phone: (410) 706-7514
Fax: (410) 706-5017
Research Interests
Research in my lab has two main thrusts: biomaterials engineering and imaging technologies. In the biomaterials area, our current focus is the link between molecular chirality and material mechanical properties. We are also exploiting chirality to create biomaterials with novel mechanical properties for cell growth and differentiation. In the imaging area, we develop imaging agents for multi-color F-19 MRI. We are also working a MRI technology to evaluate the mechanical properties of soft materials and biological tissues.
Top- Kimmel Scholar Award in cancer research (2004)
- Presidential Early Career Award for Scientists and Engineers (PECASE) for biomaterials research (2005)
Selected Refereed Publications
Hyland, L.L., Taraban, M.B., Hammouda, B., Yu, Y.B. (2012) Viscoelastic Properties and Nano-scale Structures of Composite Oligopeptide-Polysaccharide Hydrogels. Biopolymers, 97, 177-188.
Taraban, M.B., Weerasekare, G.M., Trewhella,J., Shi, X., Jeong, E.K., Yu, Y.B. (2012) Effects of Gadolinium Chelate on the Evolution of the Nanoscale Structure in Peptide Hydrogels. Biopolymers (Pept. Sci.)98, 50-58.
Feng, Y., Taraban, M.B., Yu, Y.B. (2011) Linear Dependency of NMR Relaxation Rates on Shear Modulus in Hydrogels. Soft Matter, 7, 9890-9893.
Feng, Y., Lee, M., Taraban, M.B., Yu, Y.B. (2011) Diffusion of Small Molecules inside a Peptide Hydrogel. Chem. Comm., 47, 10455-10457.
Hyland, L.L., Taraban, M.B., Hammouda, B., Yu, Y.B. (2011) Mutually Reinforced Multi-component Polysaccharide Networks. Biopolymers, 95, 840-851.
Weerasekare, G.M., Taraban, M.B., Shi, X., Jeong, E.-K., Trewhella, J., Yu, Y.B. (2011) Sol and Gel States in Peptide Hydrogels Visualized by Gd(III)-enhanced MRI. Biopolymers (Pept. Sci.) 96, 734-743.
Jiang, Z.-X., Feng, Y., Yu, Y.B. (2011) Fluorinated Paramagnetic Chelates as Potential Multi-chromic 19F Tracer Agents. Chem. Comm. 47, 7233-7235.
Joyner, K.; Wang, W., Yu, Y.B. (2011) The Effect of Column and Eluent Fluorination on the Retention and Separation of non-Fluorinated Amino Acids and Proteins by HPLC. J. Fluorine Chem. 132, 114-122.
Taraban, M.B.; Ramachandran, S.; Gryczynski, I.; Gryczynski, Z.; Trewhella, J., Yu, Y. B. (2011) Effects of Chain Length on Oligopeptide Hydrogelation, Soft Matter, 7, 2624-2631.
Ramachandran, S., Taraban, M.B., Trewhella, J., Gryczynski, I., Gryczynski, Z., Yu, Y.B. (2010) Effects of Temperature during Assembly on the Structure and Mechanical Properties of Peptide-based Materials. Biomacromolecules, 11, 1502-1506.
Jiang, Z.-X., Yu, Y.B. (2010) Fluorous Mixture Synthesis of Asymmetric Bispherical Dendimers. J. Org. Chem. 75, 2044 - 2049.
Jiang, Z.-X.; Liu, X.; Jeong, E.K., Yu, Y.B. (2009) Symmetry-guided Design and Fluorous Synthesis of a Stable and Rapidly Excreted Imaging Tracer for 19F MRI. Angew. Chem. Int. Ed. 48, 4755-4758.
