Assistant Professor Ian White
Affiliate, Chemical Physics Program
Affiliate, Maryland Pathogen Research Institute
Member, Maryland Nanocenter
Ph.D., Stanford University, 2002
Room 2216 Kim Engineering Building
E-mail: ianwhite@umd.edu
Phone: (301) 405-6230
Fax: (301) 405-9953
Research Interests
Disease detection, optical biosensors, ring resonators, SERS, lab-on-a-chip.
Current Research
The aim of our research group is to develop tools for the diagnosis and study of disease at the molecular level using highly-integrated biosensing techniques. Disease detection at the molecular level is critical for early diagnosis as well as for low-cost monitoring of treatment progress. Also, access at the molecular level is important for discovering the origins, the progression mechanisms, and the cure for a disease. Photonics technologies offer unique capabilities to probe samples at the molecular level in low-cost, high-density component configurations.
One tool that we are developing uses a capillary ring resonator (CRR) as a microfluidic photonic biosensor that performs label-free molecular detection (i.e., fluorescent or radioactive labels are not used in the sensing mechanism). The optofluidic nature of the CRR is well-suited for lab-on-a-chip integration. Such an implementation leads to a low-cost device capable of performing highly complex molecular biology analyses, and can speed the process of scientific discovery in many fields, especially public health.
Selected Refereed Publications
I. M. White and X. Fan, "On the performance quantification of resonant refractive index sensors," Optics Express 16, 1020-1028 (2008).
I. M. White, J. Gohring, and X. Fan, "SERS-based detection in an optofluidic ring resonator platform," Optics Express 15, 17433-17442 (2007).
I. M. White, J. Gohring, Y. Sun, G. Yang, S. Lacey, and X. Fan, "Versatile waveguide-coupled opto-fluidic devices based on liquid core optical ring resonators," Applied Physics Letters 94, 241104 (2007).
I. M. White, J. D. Suter, H. Oveys, X. Fan, T. L. Smith, J. Zhang, B. J. Koch, and M. A. Haase, "Universal coupling between metal-clad waveguides and optical ring resonators," Optics Express 15, 646-651 (2007).
I. M. White, H. Zhu, J. D. Suter, N. M. Hanumegowda, H. Oveys, M. Zourob, and X. Fan, "Refractometric Sensors for Lab-on-a-Chip Based on Optical Ring Resonators," IEEE Sensors Journal 7, 28-35 (2007).
I. M. White, H. Oveys, X. Fan, T. L. Smith, and J. Zhang, "Integrated Multiplexed Biosensors Based on Liquid Core Optical Ring Resonators and Anti-Resonant Reflecting Optical Waveguide," Applied Physics Letters 89, 191106 (2006).
I. M. White, H. Oveys, and X. Fan, "Increasing the enhancement of SERS with dielectric microsphere resonators," April 1 issue of Spectroscopy (2006).
I. M. White, H. Oveys, and X. Fan, "Liquid Core Optical Ring Resonator Sensors," Optics Letters 31, 1319-1321 (2006).
