Assistant Professor Adam Hsieh

Lab Director, Orthopaedic Mechanobiology Lab
Ph.D., University of California, San Diego, 2000

Room 3242 Jeong H. Kim Engineering Building
E-mail: hsieh@umd.edu
Phone: (301) 405-7397
Fax: (301) 314-9477

Research Interests

Orthopaedic biomechanics; soft tissue mechanobiology; mechanisms of intervertebral disc degeneration; mechanobiologic strategies for developing spatially-complex tissue engineered constructs.

Recent Publications

Hsieh AH, Wagner DR, Cheng LY, Lotz JC. "Dependence of mechanical behavior of the murine tail disc on regional material properties - a parametric finite element study." ASME J Biomech Eng 127(7): 1158-1167, 2005.

McKean JM, Hsieh AH, Sung KL. "Epidermal growth factor differentially affects integrin-mediated adhesion and proliferation of ACL and MCL fibroblasts." Biorheology 41: 139-152, 2004.

Hsieh AH, Lotz JC. "Prolonged spinal loading induces matrix metalloproteinase-2 activation in intervertebral discs." Spine 28: 1781-1788, 2003.

Lotz JC, Hsieh AH, Walsh AL, Palmer EI, Chin JR. "Mechanobiology of the intervertebral disc." Biochem Soc Trans 30: 853-858, 2002.

Hsieh AH, Sah RL, Paul Sung KL. "Biomechanical regulation of type I collagen gene expression in ACLs in organ culture." J Orthop Res 20: 325-331, 2002.

Hsieh AH, Tsai CM, Ma QJ, Lin T, Banes AJ, Villarreal FJ, Akeson WH, Sung KL. "Time-dependent increases in type-III collagen gene expression in medical collateral ligament fibroblasts under cyclic strains." J Orthop Res 18: 220-227, 2000.

Scientific and Professional Membership
Organizer, 12th Annual Computational Methods in Orthopaedic Biomechanics (Pre-ORS), 2004

Honors and Awards

NIH Ruth L. Kirchstein National Research Service Award, 2001.