Event

Bioengineering Seminar Series: Joseph P. Y. Kao

Friday, April 9, 2010
11:00 a.m.
Room 2110, Chemical and Nuclear Engineering Bldg.
Professor Greg Payne
payne@umbi.umd.edu

Targeted In Vivo Contrast Generation and Electron Paramagnetic Resonance Imaging (EPRI)

Presented by Joseph P. Y. Kao
Professor
Medical Biotechnology Center, University of Maryland Biotechnology Institute, and
Department of Physiology, University of Maryland School of Medicine

Magnetic resonance imaging (MRI) detects protons, which are vastly abundant in the body. In contrast, EPRI detects molecules bearing unpaired electrons—i.e., free radicals—which are normally extremely short-lived and scarce. Therefore, to visualize specific tissues by EPRI, so-called "spin probes," which are stable free radicals, must be targeted to the tissue of interest. We will review the basics of EPRI as well as the use of immuno-liposomes to target delivery of contrast agents for imaging.

Audience: Graduate  Faculty  Post-Docs