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Bioengineering Seminar Series: Wonmuk Hwang
Friday, October 31, 2008
11:00 a.m.
Room 2108, Chemical and Nuclear Engineering Bldg.
For More Information:
Professor Joonil Seog
(301) 405- 1885

Analyzing the Assembly and Mechanics of the Molecular Building Blocks of Life

Presented by Wonmuk Hwang
Assistant Professor, Biomedical Engineering
Texas A&M University

At the core of all physiological functions and chemical activities of biomolecules are biophysical or biomechanical processes such as folding, conformational dynamics, and assembly of individual proteins mediated by a cohort of intra- and inter-molecular forces. While bulk studies have lead to staggering developments in biochemistry, nanomechanics of biomolecules and their assemblies has only begun to be explored as relevant experimental and computational tools have become available in recent years. Due to the complex nature of these systems, it is essential to use computer simulations for developing atomistic insights. In this regard, we have made a number of contributions for understanding mechanical elements of the cell, which include biofilaments (alpha-helix, amyloid, and collagen) and motor proteins (kinesin). In this talk, these advances, together with relevant experiments, will be presented. These exemplify molecular biomechanics as an emerging area that will bring about a new paradigm of describing biomolecular processes, which are important in health, disease, as well as in bioengineering applications.

This Event is For: Graduate • Faculty • Post-Docs

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